Neuromyelitis optica and pregnancy

Neuromyelitis optica and pregnancy

Author Fragoso, Yara Dadalti Google Scholar
Adoni, Tarso Google Scholar
Bichuetti, Denis Bernardi Autor UNIFESP Google Scholar
Bidin Brooks, Joseph Bruno Google Scholar
Brito Ferreira, Maria Lucia Google Scholar
Lobato Oliveira, Enedina Maria Autor UNIFESP Google Scholar
Silva Oliveira, Celso Luis Google Scholar
Felix Ribeiro, Sonia Beatriz Google Scholar
Silva, Alex Eduardo Google Scholar
Siquineli, Fabio Google Scholar
Institution Univ Metropolitana Santos UNIMES
Hosp Sirio Libanes
Universidade Federal de São Paulo (UNIFESP)
Hosp Restauracao
Univ Fed Triangulo Mineiro
Univ Reg Blumenau
Abstract Less than a hundred cases of pregnancies in women with neuromyelitis optica (NMO) have been published in the world. the aim of the present study was to add the Brazilian experience to this subject. Cases of women with NMO who became pregnant, or who developed NMO soon after pregnancy, were included. Retrospective analysis of medical data from these patients was carried out by the neurologist responsible for the case. Seventeen cases of pregnancies (16 full-term pregnancies, one miscarriage) were identified. the relapse rate of demyelinating events in the first trimester after pregnancy was significantly higher than at any other time. Disability progression was significantly worse 1 year after delivery. Pregnancy negatively influenced the disease course of NMO in these women. These results are similar to those of other authors, although the total number of cases so far described is still small. Obstetricians must be aware of the potential complications of a pregnancy in a woman who has NMO.
Keywords Neuromyelitis optica
Devic's disease
Pregnancy
Disability
Language English
Date 2013-10-01
Published in Journal of Neurology. Heidelberg: Springer Heidelberg, v. 260, n. 10, p. 2614-2619, 2013.
ISSN 0340-5354 (Sherpa/Romeo, impact factor)
Publisher Springer
Extent 2614-2619
Origin http://dx.doi.org/10.1007/s00415-013-7031-y
Access rights Closed access
Type Article
Web of Science ID WOS:000325639400021
URI http://repositorio.unifesp.br/handle/11600/36797

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