Boston type 1 keratoprosthesis outcomes in ocular burns

Boston type 1 keratoprosthesis outcomes in ocular burns

Author Magalhaes, Fernanda Pedreira Autor UNIFESP Google Scholar
Hirai, Flavio Eduardo Autor UNIFESP Google Scholar
Sousa, Luciene Barbosa de Autor UNIFESP Google Scholar
Oliveira, Lauro Augusto de Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract Purpose: To report the outcomes of Boston type I keratoprosthesis (BKPro) in the management of ocular burn injuries. Methods: This was a prospective study including all cases of BKPro implantation for ocular burns at the External Diseases and Cornea Service of the Federal University of São Paulo, between February 2008 and February 2010. Ten patients (10 eyes) were enrolled. Procedures performed to manage ocular injury were identified, and data were collected regarding patients' ocular history, surgical procedure(s) performed, and postoperative outcomes, including visual acuity, retention, complications and required surgical procedures. Results: A total of 11 Type 1 BKPro were implanted in 10 eyes of 10 patients. the mean follow-up period was 25.7 +/- 10.8months. Preoperative best-corrected visual acuity (BCVA) ranged from count fingers to light perception. Postoperative BCVA was better than 20/200 in 90% of the patients and better than 20/60 in 60% of the patients. the overall BKPro retention rate was 90%. the most common complications were retroprosthetic membrane formation (50%) and persistent corneal epithelial defect evolving to corneal melting (40%). Patients who underwent ocular surface procedures such as limbal transplantation prior to BKPRo implantation had a lower incidence of corneal melting/thinning (p=0.07), although this was not statistically significant. Conclusion: the anatomical and functional results identified in this study support the use of BKPro in managing bilateral limbal stem cell deficiency secondary to ocular burns.
Keywords chemical burn
ocular injury
Language English
Sponsor Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Date 2013-09-01
Published in Acta Ophthalmologica. Hoboken: Wiley-Blackwell, v. 91, n. 6, p. e432-e436, 2013.
ISSN 1755-375X (Sherpa/Romeo, impact factor)
Publisher Wiley-Blackwell
Extent e432-e436
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000323201500003

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