Juvenile myoclonic epilepsy: Psychiatric comorbidity and impact on outcome

Juvenile myoclonic epilepsy: Psychiatric comorbidity and impact on outcome

Author Araujo Filho, Gerardo Maria de Autor UNIFESP Google Scholar
Targas Yacubian, Elza Marcia Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract Juvenile myoclonic epilepsy (JME) is a well-defined age-related idiopathic epilepsy syndrome. Past studies have emphasized the difficulties in the treatment of patients with JME, which have been attributed to some specific psychiatric, psychological, and psychosocial characteristics. These aspects have aroused a significant amount of interest in the last two decades. in this article, the available studies that investigated the prevalence of psychiatric disorders (PDs) in JME and its impact on seizure outcome were reviewed in order to provide an update to clinicians about these two important aspects associated with this common epilepsy syndrome. the review disclosed a high prevalence of PDs in patients with JME, particularly mood, anxiety, and personality disorders. in addition, most recent studies have also observed that overall prevalence of PDs in JME has not shown statistically significant differences when compared with TLE, an epilepsy syndrome where the psychiatric aspects are most frequently studied. Taken together, data regarding the prevalence of PDs and their possible consequences on seizure outcome on JME indicate that special attention should be directed to psychological disturbances and psychiatric symptoms in this epilepsy syndrome. the early recognition and treatment of psychiatric symptoms, as well as psychological disturbances and psychosocial difficulties, should be considered fundamental to JME prognosis.This article is part of a supplemental special issue entitled Juvenile Myoclonic Epilepsy: What is it Really? (C) 2013 Elsevier Inc. All rights reserved.
Keywords Juvenile myoclonic epilepsy
Psychiatric disorders
Personality traits
Seizure outcome
Language English
Sponsor Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Date 2013-07-01
Published in Epilepsy & Behavior. San Diego: Academic Press Inc Elsevier Science, v. 28, p. S74-S80, 2013.
ISSN 1525-5050 (Sherpa/Romeo, impact factor)
Publisher Elsevier B.V.
Extent S74-S80
Origin http://dx.doi.org/10.1016/j.yebeh.2013.03.026
Access rights Closed access
Type Review
Web of Science ID WOS:000321165800017
URI http://repositorio.unifesp.br/handle/11600/36508

Show full item record


File Size Format View

There are no files associated with this item.

This item appears in the following Collection(s)




My Account