Sudden unexpected death in epilepsy: From the lab to the clinic setting

Sudden unexpected death in epilepsy: From the lab to the clinic setting

Author Terra, Vera C. Google Scholar
Cysneiros, Roberta Monterazzo Autor UNIFESP Google Scholar
Cavalheiro, Esper A. Autor UNIFESP Google Scholar
Scorza, Fulvio A. Autor UNIFESP Google Scholar
Institution Universidade de São Paulo (USP)
Univ Presbiteriana Mackenzie
Universidade Federal de São Paulo (UNIFESP)
Abstract Sudden unexpected death in epilepsy (SUDEP) is defined as sudden, unexpected, witnessed or unwitnessed, non-traumatic, and non-drowning death in a patient with epilepsy. Sudden unexpected death in epilepsy is probably the most common cause of epilepsy-related deaths. Many predisposing and initiating factors may coexist and contribute to SUDEP, but the mechanisms are poorly understood. Cardiac and respiratory deregulation seems to have a major role in SUDEP. Here, we review several advances in understanding the mechanisms involved in SUDEP.This article is part of a Special Issue entitled the Future of Translational Epilepsy Research. (c) 2012 Elsevier Inc. All rights reserved.
Keywords Epilepsy
Sudden death
Risk factors
Language English
Date 2013-03-01
Published in Epilepsy & Behavior. San Diego: Academic Press Inc Elsevier Science, v. 26, n. 3, p. 415-420, 2013.
ISSN 1525-5050 (Sherpa/Romeo, impact factor)
Publisher Elsevier B.V.
Extent 415-420
Origin http://dx.doi.org/10.1016/j.yebeh.2012.12.018
Access rights Closed access
Type Review
Web of Science ID WOS:000316663900027
URI http://repositorio.unifesp.br/handle/11600/36041

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