Acidóse tubular renal distal manifestando-se com rabdomiólise

Acidóse tubular renal distal manifestando-se com rabdomiólise

Alternative title Distail renal tubular acidosis manifesting with rhabdomyolysis
Author Zanoteli, Edmar Autor UNIFESP Google Scholar
Oliveira, Acary Souza Bulle Autor UNIFESP Google Scholar
Tengan, Célia Harumi Autor UNIFESP Google Scholar
Morita, Maria da Penha Ananias Autor UNIFESP Google Scholar
Schmidt, Beny Autor UNIFESP Google Scholar
Gabbai, Alberto Alain Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract Severe hypokalemia is an uncommon cause of rhabdomyolysis. We describe a patient, 28-year-old woman, with distal renal tubular acidosis (DRTA) who developed severe hypokalemia and rhabdomyolysis. Muscle biopsy shows focal muscular necrosis mainly in type II muscle fibers and mild macrophagic reaction. After correcting the acidosis with oral administration of alkalinizing salts, clinical and laboratory improvement was seen. This clearly establish a causal realtionship between the positive acid balance, hypokalemia and the muscular manifestation in DRTA.

A hipocalemia severa é causa incomum de rabdomiólise. Descreve-se o caso de urna paciente de 28 anos com acidóse tubular renal distal, que desenvolveu hipocalemia severa com consequente rabdomiólise. O estudo histológico do músculo evidenciou áreas focais de necrose muscular predominando em fibras do tipo II, com discreta reação macrofágica. A melhora clínica e laboratorial apresentada pela paciente ocorreu após a normalização do potássio sérico, tendo sido fundamental, neste caso, a correção da acidóse metabólica.
Keywords hypokalemia
rhabdomyolysis
renal tubular acidosis
hipocalemia
rabdomiólise
acidóse tubular renal
Language Portuguese
Date 1994-12-01
Published in Arquivos de Neuro-Psiquiatria. Academia Brasileira de Neurologia - ABNEURO, v. 52, n. 4, p. 549-553, 1994.
ISSN 0004-282X (Sherpa/Romeo)
Publisher Academia Brasileira de Neurologia - ABNEURO
Extent 549-553
Origin http://dx.doi.org/10.1590/S0004-282X1994000400016
Access rights Open access Open Access
Type Article
SciELO ID S0004-282X1994000400016 (statistics in SciELO)
URI http://repositorio.unifesp.br/handle/11600/360

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