Ankle-brachial index as a predictor of coronary disease events in elderly patients submitted to coronary angiography

Ankle-brachial index as a predictor of coronary disease events in elderly patients submitted to coronary angiography

Author Papa, Eduardo D. E. Autor UNIFESP Google Scholar
Helber, Izo Autor UNIFESP Google Scholar
Ehrlichmann, Manes R. Google Scholar
Rodrigues Alves, Claudia Maria Autor UNIFESP Google Scholar
Makdisse, Marcia Google Scholar
Matos, Livia N. Autor UNIFESP Google Scholar
Borges, Jairo Lins Autor UNIFESP Google Scholar
Lopes, Renato D. Google Scholar
Stefanini, Edson Autor UNIFESP Google Scholar
Carvalho, Antonio Carlos Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Hosp Israelita Albert Einstein
Duke Univ
Abstract OBJECTIVES: To correlate the importance of the ankle-brachial index in terms of cardiovascular morbimortality and the extent of coronary arterial disease amongst elderly patients without clinical manifestations of lower limb peripheral arterial disease.METHODS: We analyzed prospective data from 100 patients over 65 years of age with coronary arterial disease, as confirmed by coronary angiography, and with over 70% stenosis of at least one sub-epicardial coronary artery. We measured the ankle-brachial index immediately after coronary angiography, and a value of <0.9 was used to diagnose peripheral arterial disease.RESULTS: the patients' average age was 77.4 years. the most prevalent risk factor was hypertension (96%), and the median late follow-up appointment was 28.9 months. the ankle-brachial index was <0.9 in 47% of the patients, and a low index was more prevalent in patients with multiarterial coronary disease compared to patients with uniarterial disease in the same group. Using a bivariate analysis, only an ankle-brachial index of,0.9 was a strong predictive factor for cardiovascular events, thereby increasing all-cause deaths and fatal and non-fatal acute myocardial infarctions two-to three-fold.CONCLUSION: in elderly patients with documented coronary disease, a low ankle-brachial index (<0.9) was associated with the severity and extent of coronary arterial disease, and in late follow-up appointments, a low index was correlated with an increase in the occurrence of major cardiovascular events.
Keywords Peripheral Artery Disease
Prognosis
Coronary artery Disease
Ankle Brachial Index
Elderly
Language English
Date 2013-01-01
Published in Clinics. São Paulo: Hospital Clinicas, Univ São Paulo, v. 68, n. 12, p. 1481-1487, 2013.
ISSN 1807-5932 (Sherpa/Romeo, impact factor)
Publisher Hospital Clinicas, Univ São Paulo
Extent 1481-1487
Origin http://dx.doi.org/10.6061/clinics/2013(12)02
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000329985900002
SciELO ID S1807-59322013001201481 (statistics in SciELO)
URI http://repositorio.unifesp.br/handle/11600/35765

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