Helium-neon laser improves skin repair in rabbits

Helium-neon laser improves skin repair in rabbits

Author Peccin, Maria Stella Autor UNIFESP Google Scholar
Muniz Renno, Ana Claudia Autor UNIFESP Google Scholar
Oliveira, Flavia de Autor UNIFESP Google Scholar
Giusti, Paulo Ricardo Google Scholar
Ribeiro, Daniel Araki Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract The purpose of this study was to evaluate the influence of helium-neon laser on skin injury in rabbits. for this purpose, 15 New Zealand rabbits underwent bilateral skin damage in leg. Helium-neon laser light, at a fluence of 6 J/cm(2) and wavelength of 632.8 nm, was applied on the left legs (laser group). the right leg lesions (control group) served as negative control. All sections were histopathologically analyzed using HE sections. the results showed little infiltration of inflammatory cells, with proliferation of fibroblasts forming a few fibrous connective tissue after 1 week post-injury. the lesion on the 3rd week was characterized by granulation tissue, which formed from proliferated fibrous connective tissue, congested blood vessels and mild mononuclear cell infiltration. On the 5th week, it was observed that debris material surrounded by a thick layer of connective tissue and dense collage, fibroblasts cells present in the dermis covered by a thick epidermal layer represented by keratinized epithelium. Taken together, our results suggest that helium-neon laser is able to improve skin repair in rabbits at early phases of recovery.
Keywords helium-neon laser
rabbit
skin
wound healing
Language English
Date 2012-12-01
Published in Journal of Cosmetic and Laser Therapy. London: Informa Healthcare, v. 14, n. 6, p. 286-289, 2012.
ISSN 1476-4172 (Sherpa/Romeo, impact factor)
Publisher Informa Healthcare
Extent 286-289
Origin http://dx.doi.org/10.3109/14764172.2012.738917
Access rights Closed access
Type Article
Web of Science ID WOS:000311897700008
URI http://repositorio.unifesp.br/handle/11600/35603

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