Chronic Exercise Promotes Alterations in the Neuroendocrine Profile of Elderly People

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dc.contributor.author Alves, E. S.
dc.contributor.author Souza, H. S.
dc.contributor.author Rosa, J. P. P.
dc.contributor.author Lira, F. S. [UNIFESP]
dc.contributor.author Pimentel, G. D.
dc.contributor.author Santos, R. V. T. [UNIFESP]
dc.contributor.author Oyama, L. M. [UNIFESP]
dc.contributor.author Damaso, A. R. [UNIFESP]
dc.contributor.author Oller do Nascimento, C. M. [UNIFESP]
dc.contributor.author Viana, V. A. R. [UNIFESP]
dc.contributor.author Boscolo, R. A. [UNIFESP]
dc.contributor.author Grassmann, V. [UNIFESP]
dc.contributor.author Santana, M. G. [UNIFESP]
dc.contributor.author Tufik, S. [UNIFESP]
dc.contributor.author Mello, M. T. de [UNIFESP]
dc.date.accessioned 2016-01-24T14:28:06Z
dc.date.available 2016-01-24T14:28:06Z
dc.date.issued 2012-12-01
dc.identifier http://dx.doi.org/10.1055/s-0032-1316294
dc.identifier.citation Hormone and Metabolic Research. Stuttgart: Georg Thieme Verlag Kg, v. 44, n. 13, p. 975-979, 2012.
dc.identifier.issn 0018-5043
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/35581
dc.description.abstract Aging and physical inactivity are 2 factors that favour the development of cardiovascular disease, metabolic syndrome, obesity, and diabetes. in contrast, adopting a habitual moderate exercise routine may be a nonpharmacological treatment alternative for neuroendocrine aging disorders. We aimed to assess the effects of moderate exercise training on the metabolic profiles of elderly people with sedentary lifestyles. Fourteen sedentary, healthy, elderly male volunteers participated in a moderate training regimen for 60 min/day, 3 days/week for 24 weeks at a work rate equivalent to their ventilatory aerobic threshold. the environment was maintained at a temperature of 23 +/- 2 degrees C, with a humidity of 60 +/- 5 %. Blood samples for analysis were collected at 3 intervals: at baseline (1 week before training began), and 3 and 6 months after training. the training promoted increased aerobic capacity (relative VO2, and time and velocity to VO(2)max; (p < 0.05)) and reduced serum alpha-MSH (p < 0.05) after 3 months of training when compared with the baseline data. in addition, serum thyroid hormone (T3 and T4) was reduced after 6 months of training compared with baseline levels. Our results demonstrate that a moderate exercise training protocol improves the metabolic profile of older people, and metabolic adaptation is dependent on time. en
dc.description.sponsorship Associacao Fundo de Incentivo a Pesquisa (AFIP)
dc.description.sponsorship Centro de Estudos em Psicobiologia and Exercicio (CEPE)
dc.description.sponsorship Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorship Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorship Universidade Federal de São Paulo (UNIFESP)
dc.format.extent 975-979
dc.language.iso eng
dc.publisher Georg Thieme Verlag Kg
dc.relation.ispartof Hormone and Metabolic Research
dc.rights Acesso restrito
dc.subject aerobic capacity en
dc.subject neuropeptides en
dc.subject aging en
dc.subject moderate training en
dc.title Chronic Exercise Promotes Alterations in the Neuroendocrine Profile of Elderly People en
dc.type Artigo
dc.contributor.institution Ctr Estudo Psicobiol Exercicio
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.contributor.institution Univ Extremo Sul Catarinense
dc.contributor.institution Universidade Estadual de Campinas (UNICAMP)
dc.contributor.institution Universidade Federal de Goiás (UFG)
dc.description.affiliation Ctr Estudo Psicobiol Exercicio, São Paulo, Brazil
dc.description.affiliation Universidade Federal de São Paulo, Dept Psicobiol, São Paulo, Brazil
dc.description.affiliation Univ Extremo Sul Catarinense, Lab Fisiol & Bioquim Exercicio, Criciuma, SC, Brazil
dc.description.affiliation Univ Estadual Campinas, Dept Med Interna, BR-13081970 Campinas, SP, Brazil
dc.description.affiliation Universidade Federal de São Paulo, Dept Biociencias, São Paulo, Brazil
dc.description.affiliation Universidade Federal de São Paulo, Escola Paulista Med, Disciplina Fisiol Nutr, Dept Fisiol, São Paulo, Brazil
dc.description.affiliation Univ Fed Goias, Goiania, Go, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo, Dept Psicobiol, São Paulo, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo, Dept Biociencias, São Paulo, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo, Escola Paulista Med, Disciplina Fisiol Nutr, Dept Fisiol, São Paulo, Brazil
dc.identifier.doi 10.1055/s-0032-1316294
dc.description.source Web of Science
dc.identifier.wos WOS:000312501800008



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