Acute pancreatitis in pediatrics: a systematic review of the literature

Acute pancreatitis in pediatrics: a systematic review of the literature

Alternative title Pancreatite aguda em pediatria: revisão sistemática da literatura
Author Mekitarian Filho, Eduardo Autor UNIFESP Google Scholar
Carvalho, Werther Brunow de Autor UNIFESP Google Scholar
Silva, Felipe Duarte Google Scholar
Institution Universidade de São Paulo (USP)
Universidade Federal de São Paulo (UNIFESP)
Hosp Israelite Albert Einstein
Hosp Santa Catarina
Abstract Objective: To describe the main epidemiological, clinical, diagnostic and treatment aspects of children with acute pancreatitis.Sources: Systematic review of MEDLINE and SciELO databases in the last 5 years about acute pancreatitis in children, as well as consultation of relevant references on the texts obtained.Summary of the findings: Cases of acute pancreatitis in children have received growing attention in recent years, and an increase in the number of cases has been reported in several studies. the main etiologies in children involve biliary disease, drug-induced pancreatitis, recurrent hereditary pancreatitis and trauma, and up to 30% of cases have no defined etiology. the diagnosis is based on the combination of clinical and laboratory aspects with the increase of acinar enzymes and radiologic tests. Initial support treatment, with proper volume replacement and correction of the metabolic disturbances, besides specific nutritional therapy, are the fundamental points in the handling of acute conditions. Long term complications are unusual, and mortality rates are inferior to the rates for the adult population.Conclusions: the early diagnosis and the appropriate handling can contribute to a better outcome for the child with pancreatitis and to prevent the immediate and late complications related to the disease. More studies are required to better explain aspects related to the clinical and radiological diagnosis of pancreatitis in children, as well as aspects related to the nutritional therapy for this age group.
Keywords Pancreatitis
pediatrics
nutritional support
morbidity
enteral nutrition
Language English
Date 2012-03-01
Published in Jornal de Pediatria. Rio de Janeiro, Rj: Soc Brasil Pediatria, v. 88, n. 2, p. 101-114, 2012.
ISSN 0021-7557 (Sherpa/Romeo, impact factor)
Publisher Soc Brasil Pediatria
Extent 101-114
Origin http://dx.doi.org/10.2223/JPED.2163
Access rights Open access Open Access
Type Review
Web of Science ID WOS:000303906000002
SciELO ID S0021-75572012000200002 (statistics in SciELO)
URI http://repositorio.unifesp.br/handle/11600/34653

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