Premature rupture of membranes before 28 weeks managed expectantly: Maternal and perinatal outcomes in a developing country

Premature rupture of membranes before 28 weeks managed expectantly: Maternal and perinatal outcomes in a developing country

Author Fernandes, G. L. Google Scholar
Torloni, M. R. Google Scholar
Hisaba, W. Jou Google Scholar
Klimke, D. Google Scholar
Novaes, J. Google Scholar
Sancovski, M. Autor UNIFESP Google Scholar
Peixoto, S. Autor UNIFESP Google Scholar
Institution Hosp Municipal Univ
Fac Med ABC
Universidade Federal de São Paulo (UNIFESP)
Abstract This study aimed to assess outcomes of expectant management for early preterm premature rupture of membranes (PPROM). This retrospective cohort involved 66 women with PPROM <28 weeks managed in a single hospital (1999-2006). Main outcomes were chorioamnionitis, severe maternal morbidity (maternal sepsis, haemorrhage/blood transfusion, hysterectomy or admission to intensive care unit), maternal mortality, low birth weight, preterm birth, neonatal infection and perinatal mortality. Mean gestational ages at PPROM and delivery were 21.7 +/- 4.2 and 28.4 +/- 5.9 weeks, respectively. Chorioamnionitis was diagnosed in 47%; no cases of severe maternal morbidity or mortality occurred. Stillbirth rate was 25.7% and >80% of infants were delivered before 34 weeks. Neonatal infection was diagnosed in 42.9% of the 49 live-births. Overall survival rate was 57.6%. Expectant management of PPROM <28 weeks resulted in high rates of chorioamnionitis and preterm deliveries but in over half of the cases, a live infant was discharged home.
Keywords Developing countries
morbidity
mortality
PPROM
Language English
Date 2012-01-01
Published in Journal of Obstetrics and Gynaecology. New York: Informa Healthcare, v. 32, n. 1, p. 45-49, 2012.
ISSN 0144-3615 (Sherpa/Romeo, impact factor)
Publisher Informa Healthcare
Extent 45-49
Origin http://dx.doi.org/10.3109/01443615.2011.609923
Access rights Closed access
Type Article
Web of Science ID WOS:000298295000013
URI http://repositorio.unifesp.br/handle/11600/34506

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