Effects of repetitive transcranial magnetic stimulation on clinical, social, and cognitive performance in postpartum depression

Effects of repetitive transcranial magnetic stimulation on clinical, social, and cognitive performance in postpartum depression

Author Myczkowski, Martin Luiz Google Scholar
Dias, Alvaro Machado Autor UNIFESP Google Scholar
Luvisotto, Tatiana Google Scholar
Arnaut, Debora Google Scholar
Bellini, Bianca Boura Google Scholar
Mansur, Carlos Gustavo Google Scholar
Renno, Joel Google Scholar
Tortella, Gabriel Google Scholar
Ribeiro, Philip Leite Google Scholar
Marcolin, Marco Antonio Google Scholar
Institution Universidade de São Paulo (USP)
Universidade Federal de São Paulo (UNIFESP)
Abstract Background: This randomized, placebo-controlled, double-blind pilot study evaluated the impact of repetitive transcranial magnetic stimulation (rTMS) on clinical, cognitive, and social performance in women suffering with postpartum depression.Methods: Fourteen patients were randomized to receive 20 sessions of sham rTMS or active 5 Hz rTMS over the left dorsolateral prefrontal cortex. Psychiatric clinical scales and a neuropsychological battery were applied at baseline (pretreatment), week 4 (end of treatment), and week 6 (follow-up, posttreatment week 2).Results: the active rTMS group showed significant improvement 2 weeks after the end of rTMS treatment (week 6) in Hamilton Depression Rating Scale (P = 0.020), Global Assessment Scale (P = 0.037), Clinical Global Impression (P = 0.047), and Social Adjustment Scale-Self Report-Work at Home (P = 0.020).Conclusion: This study suggests that rTMS has the potential to improve the clinical condition in postpartum depression, while producing marginal gains in social and cognitive function.
Keywords transcranial magnetic stimulation
postpartum depression
clinical performance
cognitive performance
social performance
Language English
Date 2012-01-01
Published in Neuropsychiatric Disease and Treatment. Albany: Dove Medical Press Ltd, v. 8, p. 491-500, 2012.
ISSN 1176-6328 (Sherpa/Romeo, impact factor)
Publisher Dove Medical Press Ltd
Extent 491-500
Origin http://dx.doi.org/10.2147/NDT.S33851
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000310194800001
URI http://repositorio.unifesp.br/handle/11600/34395

Show full item record




File

File Size Format View

There are no files associated with this item.

This item appears in the following Collection(s)

Search


Browse

Statistics

My Account