Evaluation of the clinical efficacy of minimally invasive procedures for breast cancer screening at a teaching hospital

Evaluation of the clinical efficacy of minimally invasive procedures for breast cancer screening at a teaching hospital

Author Verenhitach, Beatriz Daou Autor UNIFESP Google Scholar
Elias, Simone Autor UNIFESP Google Scholar
Patrocinio, Ana Claudia Google Scholar
Pinto Nazario, Afonso Celso Autor UNIFESP Google Scholar
Waizberg, Angela Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Universidade Federal de Uberlândia (UFU)
Abstract Aims To assess the clinical efficacy of diagnostic procedures for breast cancer at a teaching hospital using internal auditing tools and quality control measures.Methods A retrospective assessment of 500 patients who underwent core needle biopsy (wide-bore needle biopsy; WBN) of palpable or non-palpable breast nodes that were submitted for at least one cytological examination (fine needle aspiration (FNA) cytology and/or imprint of a WBN specimen). for statistical analysis the auditing tool and quality control proposed by the National Health Service breast screening programme was utilised.Results for FNA, full specificity, positive predictive value, inadequate rates and suspicious rates were satisfactory while absolute sensitivity, complete sensitivity, false negatives and false positives were unsatisfactory. for imprint, absolute sensitivity, complete sensitivity, inadequate rate from cancers and suspicious rates were satisfactory, and the remaining indicators were unsatisfactory. WBN displayed the best performance with absolute sensitivity, complete sensitivity, false negative, suspicious rates, full specificity and predictive value showing satisfactory results and only one unsatisfactory result (false positive).Conclusions Based on an overall analysis, WBN displayed the highest clinical efficacy compared with FNA and imprint, and demonstrated adequate safety for confirming the appropriate diagnosis and management of patients, ensuring the efficacy of the service.
Language English
Date 2011-10-01
Published in Journal of Clinical Pathology. London: B M J Publishing Group, v. 64, n. 10, p. 858-861, 2011.
ISSN 0021-9746 (Sherpa/Romeo, impact factor)
Publisher B M J Publishing Group
Extent 858-861
Origin http://dx.doi.org/10.1136/jclinpath-2011-200057
Access rights Closed access
Type Article
Web of Science ID WOS:000295118300005
URI http://repositorio.unifesp.br/handle/11600/34130

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