Immunohistochemical expression of types I and III collagen antibodies in the temporomandibular joint disc of human foetuses

Immunohistochemical expression of types I and III collagen antibodies in the temporomandibular joint disc of human foetuses

Author Moraes, Luis Otavio Carvalho de Autor UNIFESP Google Scholar
Lodi, Fabio Redivo Autor UNIFESP Google Scholar
Gomes, Thiago Simao Autor UNIFESP Google Scholar
Marques, Sergio Ricardo Autor UNIFESP Google Scholar
Oshima, Celina Tizuko Fujiyama Autor UNIFESP Google Scholar
Lancellotti, Carmen Lucia Penteado Google Scholar
Rodriguez-Vazquez, Jose Francisco Google Scholar
Merida-Velasco, Jose Ramon Google Scholar
Alonso, Luis Garcia Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Santa Casa São Paulo
Univ Complutense Madrid
Abstract The objective was to study the morphology of the articular disc and analyse the immunohistochemical expression of types I and III collagen markers in the temporomandibular joint (TMJ) disc of human foetuses of different gestational ages. Twenty TMJ from human foetuses supplied by Universidade Federal de Uberaba with gestational ages from 17 to 24 weeks were studied. the gestational age of the foetuses was determined by measuring the crown-rump (CR) length. Macroscopically, the foetuses were fixed in 10% formalin solution and dissected by removing the skin and subcutaneous tissue and exposing the deep structures. Immunohistochemical markers of type I and III were used to characterize the existence of collagen fibres. Analysis of the immunohistochemical markers of types I and III collagen revealed the presence of heterotypical fibril networks.
Keywords articular disc
temporomandibular joint
human foetuses
collagen
immunohistochemical
embryology
Language English
Sponsor Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Date 2011-01-01
Published in European Journal of Histochemistry. Pavia: Pagepress Publ, v. 55, n. 3, p. 127-130, 2011.
ISSN 1121-760X (Sherpa/Romeo, impact factor)
Publisher Pagepress Publ
Extent 127-130
Origin http://dx.doi.org/10.4081/ejh.2011.e24
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000300367800004
URI http://repositorio.unifesp.br/handle/11600/33239

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