Can poor sleep affect skin integrity?

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dc.contributor.author Kahan, V. [UNIFESP]
dc.contributor.author Andersen, M. L. [UNIFESP]
dc.contributor.author Tomimori, J. [UNIFESP]
dc.contributor.author Tufik, Sergio [UNIFESP]
dc.date.accessioned 2016-01-24T14:05:46Z
dc.date.available 2016-01-24T14:05:46Z
dc.date.issued 2010-12-01
dc.identifier http://dx.doi.org/10.1016/j.mehy.2010.07.018
dc.identifier.citation Medical Hypotheses. Edinburgh: Churchill Livingstone, v. 75, n. 6, p. 535-537, 2010.
dc.identifier.issn 0306-9877
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/33131
dc.description.abstract Modern society has reported a decline in sleep time in the recent decades. This reduction can increase the morbidity and mortality of several diseases and leads to an immunosuppressive state. the skin is the largest organ in the human body and collagen, its main component, has a key role in the structure and integrity of the organism. the entire sequence of events necessary during collagen formation can be affected by endogenous and exogenous factors. A variety of studies in the literature have shown that sleep plays a role in restoring immune system function and that changes in the immune response may affect collagen production. Several studies of prolonged sleep deprivation suggest a break in skin barrier function and mucous membranes. in fact, the reduction of sleep time affects the composition and integrity of various systems. Thus, we hypothesized that lack of sleep as well as other types of stress can impair skin integrity. (C) 2010 Elsevier B.V. All rights reserved. en
dc.description.sponsorship AFIP
dc.description.sponsorship Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorship Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.format.extent 535-537
dc.language.iso eng
dc.publisher Churchill Livingstone
dc.relation.ispartof Medical Hypotheses
dc.rights Acesso restrito
dc.title Can poor sleep affect skin integrity? en
dc.type Artigo
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.description.affiliation Universidade Federal de São Paulo UNIFESP, Dept Psicobiol, São Paulo, Brazil
dc.description.affiliation Universidade Federal de São Paulo UNIFESP, Dept Dermatol, São Paulo, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo UNIFESP, Dept Psicobiol, São Paulo, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo UNIFESP, Dept Dermatol, São Paulo, Brazil
dc.identifier.doi 10.1016/j.mehy.2010.07.018
dc.description.source Web of Science
dc.identifier.wos WOS:000286918300019



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