Can poor sleep affect skin integrity?

Can poor sleep affect skin integrity?

Author Kahan, V. Autor UNIFESP Google Scholar
Andersen, M. L. Autor UNIFESP Google Scholar
Tomimori, J. Autor UNIFESP Google Scholar
Tufik, Sergio Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract Modern society has reported a decline in sleep time in the recent decades. This reduction can increase the morbidity and mortality of several diseases and leads to an immunosuppressive state. the skin is the largest organ in the human body and collagen, its main component, has a key role in the structure and integrity of the organism. the entire sequence of events necessary during collagen formation can be affected by endogenous and exogenous factors. A variety of studies in the literature have shown that sleep plays a role in restoring immune system function and that changes in the immune response may affect collagen production. Several studies of prolonged sleep deprivation suggest a break in skin barrier function and mucous membranes. in fact, the reduction of sleep time affects the composition and integrity of various systems. Thus, we hypothesized that lack of sleep as well as other types of stress can impair skin integrity. (C) 2010 Elsevier B.V. All rights reserved.
Language English
Sponsor AFIP
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Date 2010-12-01
Published in Medical Hypotheses. Edinburgh: Churchill Livingstone, v. 75, n. 6, p. 535-537, 2010.
ISSN 0306-9877 (Sherpa/Romeo, impact factor)
Publisher Churchill Livingstone
Extent 535-537
Origin http://dx.doi.org/10.1016/j.mehy.2010.07.018
Access rights Closed access
Type Article
Web of Science ID WOS:000286918300019
URI http://repositorio.unifesp.br/handle/11600/33131

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