Absence of gender effect on amygdala volume in temporal lobe epilepsy

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dc.contributor.author Silva, Ivaldo [UNIFESP]
dc.contributor.author Lin, Katia
dc.contributor.author Jackowski, Andrea P. [UNIFESP]
dc.contributor.author Centeno, Ricardo da Silva [UNIFESP]
dc.contributor.author Pinto, Magali L. [UNIFESP]
dc.contributor.author Carrete, Henrique [UNIFESP]
dc.contributor.author Yacubian, Elza Márcia Targas [UNIFESP]
dc.contributor.author Amado, Debora [UNIFESP]
dc.date.accessioned 2016-01-24T14:05:39Z
dc.date.available 2016-01-24T14:05:39Z
dc.date.issued 2010-11-01
dc.identifier http://dx.doi.org/10.1016/j.yebeh.2010.08.031
dc.identifier.citation Epilepsy & Behavior. San Diego: Academic Press Inc Elsevier Science, v. 19, n. 3, p. 501-503, 2010.
dc.identifier.issn 1525-5050
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/33055
dc.description.abstract Sexual dimorphism has already been described in temporal lobe epilepsy with mesial temporal sclerosis (TLE-MTS). This study evaluated the effect of gender on amygdala volume in patients with TLE-MTS. One hundred twenty-four patients with refractory unilateral or bilateral TLE-MTS who were being considered for epilepsy surgery underwent a comprehensive presurgical evaluation and MRI. Amygdalas of 67 women (27 with right; 32 with left, and 8 with bilateral TLE) and 57 men (22 with right, 30 with left, and 5 with bilateral TLE) were manually segmented. Significant ipsilateral amygdala volume reduction was observed for patients with right and left TLE. No gender effect on amygdala volume was observed. Contralateral amygdalar asymmetry was observed for patients with right and left TLE. Although no gender effect was observed on amygdala volume, ipsilateral amygdala volume reductions in patients with TLE might be related to differential rates of cerebral maturation between hemispheres. (C) 2010 Elsevier Inc. All rights reserved. en
dc.description.sponsorship Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorship Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.description.sponsorship Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorship ClnAPCe
dc.format.extent 501-503
dc.language.iso eng
dc.publisher Elsevier B.V.
dc.relation.ispartof Epilepsy & Behavior
dc.rights Acesso restrito
dc.subject Temporal lobe epilepsy en
dc.subject Mesial temporal lobe sclerosis en
dc.subject Gender en
dc.subject Amygdala en
dc.subject Magnetic resonance imaging en
dc.title Absence of gender effect on amygdala volume in temporal lobe epilepsy en
dc.type Artigo
dc.rights.license http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.contributor.institution HGCR
dc.description.affiliation Universidade Federal de São Paulo UNIFESP, Dept Gynecol, BR-04038031 São Paulo, Brazil
dc.description.affiliation HGCR, Ctr Epilepsia Santa Catarina CEPESC, Florianopolis, SC, Brazil
dc.description.affiliation Universidade Federal de São Paulo UNIFESP, Dept Psychiat, São Paulo, Brazil
dc.description.affiliation Universidade Federal de São Paulo UNIFESP, Dept Neurol, São Paulo, Brazil
dc.description.affiliation Universidade Federal de São Paulo UNIFESP, Dept Diagnost Radiol, São Paulo, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo UNIFESP, Dept Gynecol, BR-04038031 São Paulo, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo UNIFESP, Dept Psychiat, São Paulo, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo UNIFESP, Dept Neurol, São Paulo, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo UNIFESP, Dept Diagnost Radiol, São Paulo, Brazil
dc.identifier.doi 10.1016/j.yebeh.2010.08.031
dc.description.source Web of Science
dc.identifier.wos WOS:000285451600052



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