Grade II atypical choroid plexus papilloma with normal karyotype

Grade II atypical choroid plexus papilloma with normal karyotype

Author Brassesco, Maria Sol Google Scholar
Valera, Elvis Terci Google Scholar
Becker, Aline Paixao Google Scholar
Oliveira, Ricardo Santos Google Scholar
Scrideli, Carlos Alberto Google Scholar
Machado, Helio Rubens Google Scholar
Tone, Luiz Gonzaga Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Universidade de São Paulo (USP)
Abstract Cytogenetic studies of atypical choroid plexus papillomas (CPP) have been poorly described. in the present report, the cytogenetic investigation of an atypical CPP occurring in an infant is detailed.CPP chromosome preparations were analyzed by giemsa-trypsin-banding (GTG-banding) and comparative genome hybridization (CGH).Conventional karyotype analysis of tumor culture showed a normal chromosome complement. the results were confirmed by CGH, showing normal hybridization patterns for the sample.To date, the few atypical CPPs described in the literature have shown disparate cytogenetic information. This is the first report of a normal chromosome complement in atypical CPP. the heterogenic genetic features observed in these small series may reflect the diverse genetic background of choroid plexus tumors in children.
Keywords Choroid plexus
Language English
Sponsor Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Grant number FAPESP: 06/04827-3
FAPESP: 07/54236-4
FAPESP: 07/04065-9
Date 2009-12-01
Published in Childs Nervous System. New York: Springer, v. 25, n. 12, p. 1623-1626, 2009.
ISSN 0256-7040 (Sherpa/Romeo, impact factor)
Publisher Springer
Extent 1623-1626
Access rights Closed access
Type Article
Web of Science ID WOS:000271396800015

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