Factors associated with health-related quality of life after successful kidney transplantation: a population-based study

Factors associated with health-related quality of life after successful kidney transplantation: a population-based study

Author Bohlke, Maristela Google Scholar
Marini, Stela S. Google Scholar
Rocha, Marcos Google Scholar
Terhorst, Lisoneide Google Scholar
Gomes, Rafael H. Google Scholar
Barcellos, Franklin C. Google Scholar
Irigoyen, Maria Claudia C. Autor UNIFESP Google Scholar
Sesso, Ricardo Autor UNIFESP Google Scholar
Institution Univ Catolica Pelotas
Universidade de São Paulo (USP)
Universidade Federal de São Paulo (UNIFESP)
Abstract Kidney transplantation improves the quality of life of end-stage renal disease patients. the quality of life benefits, however, pertain to patients on average, not to all transplant recipients. the aim of this study was to identify factors associated with health-related quality of life after kidney transplantation.Population-based study with a cross-sectional design was carried out and quality of life was assessed by SF-36 Health Survey Version 1. A multivariate linear regression model was constructed with sociodemographic, clinical and laboratory data as independent variables.Two hundred and seventy-two kidney recipients with a functioning graft were analyzed. Hypertension, diabetes, higher serum creatinine and lower hematocrit were independently and significantly associated with lower scores for the SF-36 oblique physical component summary (PCSc). the final regression model explained 11% of the PCSc variance. the scores of oblique mental component summary (MCSc) were worse for females, patients with a lower income, unemployed and patients with a higher serum creatinine. the regression model explained 9% of the MCSc variance.Among the studied variables, comorbidity and graft function were the main factors associated with the PCSc, and sociodemographic variables and graft function were the main determinants of MCSc. Despite comprehensive, the final regression models explained only a little part of the heath-related quality of life variance. Additional factors, such as personal, environmental and clinical ones might influence quality of life perceived by the patients after kidney transplantation.
Keywords Health-related quality of life
Kidney transplantation
Population-based study
Outcome
Language English
Date 2009-11-01
Published in Quality of Life Research. Dordrecht: Springer, v. 18, n. 9, p. 1185-1193, 2009.
ISSN 0962-9343 (Sherpa/Romeo, impact factor)
Publisher Springer
Extent 1185-1193
Origin http://dx.doi.org/10.1007/s11136-009-9536-5
Access rights Closed access
Type Article
Web of Science ID WOS:000270650900007
URI http://repositorio.unifesp.br/handle/11600/31919

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