Cytogenetic biomonitoring in patients exposed to dental X-rays: comparison between adults and children

Cytogenetic biomonitoring in patients exposed to dental X-rays: comparison between adults and children

Author Ribeiro, Daniel Araki Autor UNIFESP Google Scholar
Oliveira, G. de Google Scholar
Castro, Gláucia Monteiro de Autor UNIFESP Google Scholar
Angelieri, F. Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Univ Metodista São Paulo
Abstract Objectives: the aim of the present study was to comparatively evaluate the DNA damage (micronucleus) and cellular death (pyknosis, karyolysis and karyorrhexis) of exfoliated buccal mucosa cells from children and adults following dental X-ray exposure.Methods: A total of 17 adults and 17 children submitted to panoramic dental radiography were included in this study.Results: the results indicated no statistically significant differences (P > 0.05) in children's micronucleated oral mucosa cells before and after dental X-ray exposure. in the same way, no mutagenic effects were observed in adults following X-ray exposure. On the other hand, X-rays increased other nuclear alterations closely related to cytotoxicity such as karyorrhexis, pyknosis and karyolysis in both groups. the comparative analysis between children and adults demonstrated no statistically significant differences in micronucleus frequency or (P > 0.05).Conclusions: in summary, these data indicate that dental paroramic radiography may not be a factor that includes chromosomal damage, but it is able to promote cytotoxicity. It seems that children are not more susceptible to the noxious activities induced by X-rays when compared with adults.
Keywords buccal mucosa cells
micronucleus test
Language English
Sponsor FAPESB
Grant number FAPESB: 07/00345-7
Date 2008-10-01
Published in Dentomaxillofacial Radiology. London: British Inst Radiology, v. 37, n. 7, p. 404-407, 2008.
ISSN 0250-832X (Sherpa/Romeo, impact factor)
Publisher British Inst Radiology
Extent 404-407
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000260169800007

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