Prospective randomized comparison of oxybutynin, functional electrostimulation, and pelvic floor training for treatment of detrusor overactivity in women

Prospective randomized comparison of oxybutynin, functional electrostimulation, and pelvic floor training for treatment of detrusor overactivity in women

Author Arruda, Raquel M. Autor UNIFESP Google Scholar
Castro, Rodrigo A. Autor UNIFESP Google Scholar
Sousa, Gabriela C. Autor UNIFESP Google Scholar
Sartori, Marair G. F. Autor UNIFESP Google Scholar
Baracat, Edmund C. Autor UNIFESP Google Scholar
Girao, Manoel J. B. C. Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract The purpose of this study is to compare the effectiveness of oxybutynin, functional electrostimulation (FES), and pelvic floor training (PFT) for treatment of women with detrusor overactivity. Sixty-four subjects were randomized to oxybutynin (n = 22), FES (n = 21), or PFT (n = 21). Women were evaluated before and after completion of 12 weeks of treatment by subjective response, voiding diary, and urodynamic test. There was subjective symptomatic improvement in 77% of the women treated with oxybutynin, 52% with FES, and 76% with PFT. Urgency resolved in 64% of women treated with oxybutynin, 52% with FES, and in 57% with PFT. Urodynamic evaluation was normal in 36% treated with oxybutynin, 57% with FES, and 52% with PFT. Maximum detrusor involuntary contraction pressure decreased in all groups (p < 0.05). All treatments were equally effective. Subjective reduction of urge-incontinence episodes was associated with symptomatic improvement.
Keywords overactive bladder
detrusor overactivity
urinary incontinence
pelvic floor training
electrical stimulation
Language English
Date 2008-08-01
Published in International Urogynecology Journal. London: Springer London Ltd, v. 19, n. 8, p. 1055-1061, 2008.
ISSN 0937-3462 (Sherpa/Romeo, impact factor)
Publisher Springer
Extent 1055-1061
Origin http://dx.doi.org/10.1007/s00192-008-0586-y
Access rights Closed access
Type Article
Web of Science ID WOS:000257726400005
URI http://repositorio.unifesp.br/handle/11600/30814

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