Chronic obstructive pulmonary disease and body mass index in five Latin America cities: the PLATINO study

Chronic obstructive pulmonary disease and body mass index in five Latin America cities: the PLATINO study

Author Oca, Maria Montes de Google Scholar
Talamo, Carlos Google Scholar
Pérez-Padilla, Rogelio Google Scholar
Jardim, José Roberto Autor UNIFESP Google Scholar
Muino, Adriana Google Scholar
Lopez, Maria Victorina Google Scholar
Valdivia, Gonzalo Google Scholar
Pertuze, Julio Google Scholar
Moreno, Dolores Google Scholar
Halbert, Ronald J. Google Scholar
Menezes, Ana Maria Baptista Google Scholar
Platino Team Google Scholar
Institution Cent Univ Venezuela
Inst Resp Dis
Universidade Federal de São Paulo (UNIFESP)
Univ Republica
Pontificia Univ Catolica Chile
Univ Calif Los Angeles
Univ Fed Pelotas Duque Caxias
Abstract Background: the body mass index (BMI) is a prognostic factor for chronic obstructive pulmonary disease (COPD). Despite its importance, little information is available regarding BMI alteration in COPD from a population-based study. We examined characteristics by BMI categories in the total and COPD populations in five Latin-American cities, and explored the factors influencing BMI in COPD.Methods: COPD was defined as a postbronchodilator forced expiratory volume in the first second/forced vital capacity (FEV(1)/FVC)< 0.70. BMI was categorized as underweight (< 20 kg/m(2)), normal weight (20 - 24.9 kg/m(2)), overweight (25.0 - 29.9 kg/m(2)), and obese (>= 30.0 kg/m(2)).Results: Interviews were completed in 5571 subjects from 6711 eligible individuals, and spirometry was performed in 5314 subjects. There were 759 subjects with COPD and 4555 without COPD. Compared with the non-COPD group, there was a higher proportion of COPD subjects in the underweight and normal weight categories, and a lower proportion in the obese category. Over one-half COPD subjects had BMI over 25 kg/m(2). No differences in BMI strata among countries were found in COPD subjects. Factors associated with lower BMI in mates with COPD were aging, current smoking, and global initiative for chronic obstructive lung disease (GOLD) stages III - IV, whereas wheeze and residing in Santiago and Montevideo were associated with higher BMI. in females with COPD, current smoking, lower education, and GOLD stages II - IV were associated with lower BMI, while dyspnea and wheeze were associated with higher BMI.Conclusions: BMI alterations are common in COPD with no significant differences among countries. Current smoking, age, GOLD stages, education level, residing in Santiago and Montevideo, dyspnea and wheeze were independently associated with BMI in COPD. (c) 2008 Elsevier B.V. All rights reserved.
Keywords chronic obstructive pulmonary disease
body mass index
epidemiology
lung function
nutritional status
prevalence
Language English
Date 2008-05-01
Published in Respiratory Medicine. London: W B Saunders Co Ltd, v. 102, n. 5, p. 642-650, 2008.
ISSN 0954-6111 (Sherpa/Romeo, impact factor)
Publisher W B Saunders Co Ltd
Extent 642-650
Origin http://dx.doi.org/10.1016/j.rmed.2007.12.025
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000256010200002
URI http://repositorio.unifesp.br/handle/11600/30606

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