Photodynamic Therapy (PDT) to treat a chronic skin wound in a dog - art. no. 68450X

Photodynamic Therapy (PDT) to treat a chronic skin wound in a dog - art. no. 68450X

Author Hage, Raduan Autor UNIFESP Google Scholar
Plapler, Helio Autor UNIFESP Google Scholar
Bitar, Renata Andrade Google Scholar
Kessel, D. Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract Photodynamic Therapy (PDT) is an emerging and promising therapeutic modality for treatment of a wide variety of malignant and nononcologic tumors, as well as in the treatment of infected skin ulcers. This study evaluated the effectiveness of the PDT to treat a chronic skin wound that had been already subjected to several clinical and surgical type treatments in a dog. the animal with an infected chronic skin wound with 8 cm diameter in the left leg received an injection of an aqueous solution of 1% methylene blue (MB) with 2% lidocaine into the lesion. After MB injection the wound was irradiated using a LED (LED-VET MMOptics(R)) with a wavelength between 600 and 700 nm, 2 cm diameter circular light beam, of 150 mW of power, light dose of 50 j/cm(2). After 3 and 6 weeks PDT was repeated and the wound was re-evaluated. Complete healing was achieved 10 weeks after the first procedure.
Keywords photodynamic therapy
wound repair
methylene blue
Language English
Date 2008-01-01
Published in Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy Xvii. Bellingham: Spie-int Soc Optical Engineering, v. 6845, p. X8450-X8450, 2008.
ISSN 0277-786X (Sherpa/Romeo, impact factor)
Publisher Spie-int Soc Optical Engineering
Extent X8450-X8450
Access rights Closed access
Type Conference paper
Web of Science ID WOS:000255356400014

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