Study of blood porphyrin spectral profile for diagnosis of tumor progression

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dc.contributor.author Courrol, Lilia Coronato
dc.contributor.author Silva, Flávia Rodrigues de Oliveira
dc.contributor.author Coutinho, Enia Lucia
dc.contributor.author Piccoli, Michelly Franca
dc.contributor.author Mansano, Ronaldo Domingues
dc.contributor.author Vieira Junior, Nilson Dias
dc.contributor.author Schor, Nestor
dc.contributor.author Bellini, Maria Helena
dc.date.accessioned 2016-01-24T13:48:38Z
dc.date.available 2016-01-24T13:48:38Z
dc.date.issued 2007-05-01
dc.identifier http://dx.doi.org/10.1007/s10895-007-0171-7
dc.identifier.citation Journal of Fluorescence. New York: Springer/plenum Publishers, v. 17, n. 3, p. 289-292, 2007.
dc.identifier.issn 1053-0509
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/29695
dc.description.abstract Renal cell carcinoma (RCC) accounts for approximately 3% of new cancer incidence and mortality in the United States. Unfortunately many RCC masses remain asymptomatic and nonpalpable until they are advanced. Diagnosis and localization of early carcinoma play an important role in the prevention and curative treatment of RCC. the autofluorescence of blood porphyrin of healthy and tumor induced in male SCID mice was analyzed using fluorescence and excitation spectroscopy. A significant contrast between normal and tumor blood could be established. Blood porphyrin fluorophore showed enhanced fluorescence band (around 630 nm) in function of the tumor growth. This indicates that either the autofluorescence intensity of the blood fluorescence may provide a good parameter for the first approximation characterization of the tumor stage. en
dc.format.extent 289-292
dc.language.iso eng
dc.publisher Springer
dc.relation.ispartof Journal of Fluorescence
dc.rights Acesso restrito
dc.subject tumor en
dc.subject phorfyrin en
dc.subject fluorescence en
dc.subject tumor growth en
dc.title Study of blood porphyrin spectral profile for diagnosis of tumor progression en
dc.type Artigo
dc.rights.license http://www.springer.com/open+access/authors+rights?SGWID=0-176704-12-683201-0
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.contributor.institution Universidade de São Paulo (USP)
dc.contributor.institution IPEN CNEN SP
dc.description.affiliation Universidade Federal de São Paulo, BR-04020041 São Paulo, Brazil
dc.description.affiliation Universidade Federal de São Paulo, Dept Ciencias Exatas, São Paulo, Brazil
dc.description.affiliation Univ São Paulo, EPUSP, LSI, BR-09500900 São Paulo, SP, Brazil
dc.description.affiliation IPEN CNEN SP, Ctr Lasers & Aplicacoes, São Paulo, SP, Brazil
dc.description.affiliation Universidade Federal de São Paulo, Div Nefrol, Dept Med, São Paulo, Brazil
dc.description.affiliation IPEN CNEN SP, Ctr Quim & Meio Ambiente, São Paulo, SP, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo, BR-04020041 São Paulo, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo, Dept Ciencias Exatas, São Paulo, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo, Div Nefrol, Dept Med, São Paulo, Brazil
dc.identifier.doi 10.1007/s10895-007-0171-7
dc.description.source Web of Science
dc.identifier.wos WOS:000246183900006



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