Correlation between temporal pole MRI abnormalities and surface ictal EEG patterns in patients with unilateral mesial temporal lobe epilepsy

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dc.contributor.author Caboclo, Luís Otávio Sales Ferreira [UNIFESP]
dc.contributor.author Garzon, Eliana [UNIFESP]
dc.contributor.author Oliveira, Pedro A. L.
dc.contributor.author Carrete Junior, Henrique [UNIFESP]
dc.contributor.author Centeno, Ricardo Silva [UNIFESP]
dc.contributor.author Bianchin, Marino Muxfeldt
dc.contributor.author Yacubian, Elza Márcia Targas [UNIFESP]
dc.contributor.author Sakamoto, Américo Ceiki [UNIFESP]
dc.date.accessioned 2016-01-24T12:41:41Z
dc.date.available 2016-01-24T12:41:41Z
dc.date.issued 2007-01-01
dc.identifier http://dx.doi.org/10.1016/j.seizure.2006.09.001
dc.identifier.citation Seizure-european Journal of Epilepsy. London: W B Saunders Co Ltd, v. 16, n. 1, p. 8-16, 2007.
dc.identifier.issn 1059-1311
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/29333
dc.description.abstract Objective: the objective of this retrospective study is to analyze ictal patterns observed during continuous Video-EEG monitoring in patients with temporal Lobe epilepsy (TLE) due to unilateral hippocampal sclerosis (HS), and to correlate these EEG patterns to temporal pole abnormalities observed on magnetic resonance imaging exams.Methods: We analyzed 147 seizures from 35 patients with TLE and unilateral HS. Ictal patterns were classified.,and correlated to signal abnormalities and volumetric measures of the temporal poles. Volume differences over 10% were considered abnormal.Results: the most frequent type of ictal pattern was rhythmic theta activity (RTA), encountered in 65.5% of the seizures. Rhythmic beta activity (RBA) was observed in 11% of the seizures, localized attenuation in 8%, interruption of epileptiform discharges in 6%, repetitive discharges in 5.5%, and rhythmic delta activity (RDA) in 4%. Sixty-six percent of the patients presented signal abnormalities in the temporal pole that were always ipsitateral to the HS. Sixty percent presented significant asymmetry of the temporal poles consisting of reduced volume that was also always ipsitateral to HS. Although patients with RTA as the predominant ictal pattern tended to present asymmetry of temporal poles (p = 0.305), the ictal EEG pattern did not correlate with temporal pole asymmetry or signal abnormalities.Conclusions: RTA is the most frequent initial ictal pattern inpatients with TLE due to unilateral HS. Temporal pole signal changes and volumetric reduction were commonly found in this group of patients, both abnormalities appearing always ipsitateral to the HS. However, neither temporal pole volume reduction nor signal abnormalities correlated with the predominant ictal pattern, suggesting that the temporal poles are not crucially involved in the process of epileptogenesis. (c) 2006 British Epilepsy Association. Published by Elsevier B.V. All rights reserved. en
dc.format.extent 8-16
dc.language.iso eng
dc.publisher W B Saunders Co Ltd
dc.relation.ispartof Seizure-european Journal of Epilepsy
dc.rights Acesso aberto
dc.subject temporal lobe epilepsy en
dc.subject hippocampal sclerosis en
dc.subject Video-EEG en
dc.subject EEG patterns en
dc.subject temporal pole en
dc.subject epilepsy surgery en
dc.title Correlation between temporal pole MRI abnormalities and surface ictal EEG patterns in patients with unilateral mesial temporal lobe epilepsy en
dc.type Artigo
dc.contributor.institution Universidade de São Paulo (USP)
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.description.affiliation Univ São Paulo, Ribeirao Preto Sch Med, Dept Neurol Psychiat & Psychol, Div Neurol, BR-14048900 Ribeirao Preto, Brazil
dc.description.affiliation Fed Univ São Paulo, Div Neurosurg, Dept Neurol & Neurosurg, São Paulo, Brazil
dc.description.affiliation Fed Univ São Paulo, Div Neuroradiol, Dept Neurol & Neurosurg, São Paulo, Brazil
dc.description.affiliation Fed Univ São Paulo, Div Neurol, Dept Neurol & Neurosurg, São Paulo, Brazil
dc.description.affiliationUnifesp Fed Univ São Paulo, Div Neurosurg, Dept Neurol & Neurosurg, São Paulo, Brazil
dc.description.affiliationUnifesp Fed Univ São Paulo, Div Neuroradiol, Dept Neurol & Neurosurg, São Paulo, Brazil
dc.description.affiliationUnifesp Fed Univ São Paulo, Div Neurol, Dept Neurol & Neurosurg, São Paulo, Brazil
dc.identifier.file WOS000243625700002.pdf
dc.identifier.doi 10.1016/j.seizure.2006.09.001
dc.description.source Web of Science
dc.identifier.wos WOS:000243625700002



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