Peptide immunization as an adjuvant to chemotherapy in mice challenged intratracheally with virulent yeast cells of Paracoccidioides brasiliensis

Peptide immunization as an adjuvant to chemotherapy in mice challenged intratracheally with virulent yeast cells of Paracoccidioides brasiliensis

Author Marques, A. F. Google Scholar
Silva, M. B. da Google Scholar
Juliano, M. A. P. Google Scholar
Travassos, Luiz Rodolpho Autor UNIFESP Google Scholar
Taborda, Carlos Pelleschi Autor UNIFESP Google Scholar
Institution Universidade de São Paulo (USP)
Universidade Federal de São Paulo (UNIFESP)
Abstract Immunization with peptide P10, derived from gp43, and chemotherapy were used together in an attempt to improve treatment of paracoccidioidomycosis and prevent relapses. the combined treatment showed an additive protective effect when administered at 48 h or 30 days after intratracheal challenge. Its use is recommended to improve regular chemotherapy and reduce the duration of treatment.
Language English
Date 2006-08-01
Published in Antimicrobial Agents and Chemotherapy. Washington: Amer Soc Microbiology, v. 50, n. 8, p. 2814-2819, 2006.
ISSN 0066-4804 (Sherpa/Romeo, impact factor)
Publisher Amer Soc Microbiology
Extent 2814-2819
Origin http://dx.doi.org/10.1128/AAC.00220-06
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000239640400030
URI http://repositorio.unifesp.br/handle/11600/29058

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