Glucose intolerance and all-cause mortality in Japanese migrants

Glucose intolerance and all-cause mortality in Japanese migrants

Author Gimeno, SGA Google Scholar
Osiro, K. Google Scholar
Matsumura, L. Google Scholar
Massimino, F. C. Google Scholar
Ferreira, SRG Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract Objective: To assess all-cause mortality in a Japanese-Brazilian community according to the categories of glucose tolerance. Study design and setting: the cohort consisted of participants examined in two phases of a follow-up study started in 1993 (n = 647). They were interviewed and submitted to an oral glucose tolerance test. Student's t-test was used to compare baseline parameters between alive and dead subjects. Cox proportional hazards model was used to estimate crude and adjusted hazard ratios (HR).Results: Seventy-one deaths occurred during the study period and a higher proportion of men (62%) was detected. Crude all-cause mortality rate was 16.2/1000 person-year. Vascular disease and cancer were the most frequent causes of deaths (77.3%). A higher mortality rate was observed in subjects with diabetes when compared with the normal glucose tolerant ones (HR: 2.0; 95% CI: 1.1-3.6), independently of age, systolic blood pressure, smoking and history of myocardial infarction.Conclusion: Also among Japanese living in the Western world, a deleterious role of fasting and 2-h plasma glucose was found on mortality especially among younger subjects. (c) 2004 Elsevier Ireland Ltd. All rights reserved.
Keywords mortality
glucose intolerance
diabetes mellitus
risk factors
Japanese migrants
plasma glucose levels
Language English
Date 2005-05-01
Published in Diabetes Research and Clinical Practice. Clare: Elsevier B.V., v. 68, n. 2, p. 147-154, 2005.
ISSN 0168-8227 (Sherpa/Romeo, impact factor)
Publisher Elsevier B.V.
Extent 147-154
Access rights Closed access
Type Article
Web of Science ID WOS:000229361900009

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