Pharmacoeconomic study of antibiotic therapy for exacerbations of chronic bronchitis and chronic obstructive pulmonary disease in Latin America

Pharmacoeconomic study of antibiotic therapy for exacerbations of chronic bronchitis and chronic obstructive pulmonary disease in Latin America

Author Miravitlles, M. Google Scholar
Jardim, José Roberto Autor UNIFESP Google Scholar
Zitto, T. Google Scholar
Rodrigues, J. E. Google Scholar
Lopez, H. Google Scholar
Institution Hosp Clin Barcelona
Universidade Federal de São Paulo (UNIFESP)
Univ Buenos Aires
Abstract Chronic obstructive pulmonary disease (COPD) and chronic bronchitis are highly prevalent diseases. Studies designed to analyze the economic impact of these diseases in Latin American countries have not previously been published. in the present study we analyzed the direct health care costs of treating patients with exacerbations of chronic bronchitis and COPD in Argentina, Brazil, Colombia, Ecuador, Mexico, Peru, and Venezuela, applying the real cost of drugs and medical acts in those 7 countries to the pattern of treatment and outcomes obtained from a study carried out in primary care settings in Spain. the mean direct health care cost ranged from US $98 in Colombia to $329 in Argentina. Most of the cost was related to failure of therapy, which accounted for 52% of the total cost of exacerbation, with the lowest rate in Colombia at 28.6% and the highest in Ecuador at 59.3% the cost of antibiotic therapy represented 19% of the total cost; the rest was owing to other drugs or medical visits.Exacerbations generate significant costs for health care systems. There are considerable variations related mainly to differences between systems. Antibiotic therapy represents a small part of the overall cost. the use of more effective antibiotics, if they can reduce failure rates, may be a cost-effective strategy.
Keywords chronic bronchitis
chronic obstructive pulmonary disease (COPD) exacerbations
antibiotics
costs
pharmacoeconomics
Language Spanish
Date 2003-12-01
Published in Archivos de Bronconeumologia. Barcelona: Ediciones Doyma S/l, v. 39, n. 12, p. 549-553, 2003.
ISSN 0300-2896 (Sherpa/Romeo, impact factor)
Publisher Ediciones Doyma S/l
Extent 549-553
Origin http://www.archbronconeumol.org/en/linkresolver/estudio-farmacoeconomico-del-tratamiento-antibiotico/S0300289603754532/
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000187621700004
URI http://repositorio.unifesp.br/handle/11600/27489

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