Fungemia in cancer patients in Brazil: Predominance of non-albicans species

Fungemia in cancer patients in Brazil: Predominance of non-albicans species

Author Nucci, M. Google Scholar
Silveira, M. I. Google Scholar
Spector, N. Google Scholar
Silveira, F. Google Scholar
Velasco, E. Google Scholar
Martins, C. A. Google Scholar
Derossi, A. Google Scholar
Colombo, A. L. Google Scholar
Pulcheri, W. Google Scholar
Institution Universidade Federal do Rio de Janeiro (UFRJ)
Universidade do Estado do Rio de Janeiro (UERJ)
Universidade Federal de São Paulo (UNIFESP)
Abstract The objective of this study was to characterize the epidemiology of candidemia in cancer patients in the city of Rio de Janeiro, Brazil. An 18-month survey of fungemia in patients with cancer was undertaken in three Hospitals in Rio de Janeiro. Forty-three episodes of candidemia were identified in 43 patients, 43 of which were episodes of candidemia; in ten cases the strains were not available for further identification of species and were excluded from this analysis. the overall distribution of fungi causing fungemia was: Candida albicans (5), Candida tropicalis (16), Candida parapsilosis (6), Candida guilliermondii (4), Candida lusitaniae (1) and Candida stellatoidea (1). Antifungal prophylaxis had been administered before the episode of fungemia in only six patients (18.2%): oral itraconazole in three patients and oral nistatin, low dose intravenous amphotericin B and oral fluconazole in one patient each. There was no difference in the presence of risk factors, clinical characteristics or in the outcome between albicans and non-albicans species, nor between Candida tropicalis and other non-albicans species. There was a clear predominance of non-albicans species, regardless of the underlying disease, antifungal prophylaxis or the presence of neutropenia.
Keywords Candidemia
cancer
epidemiology
Language English
Date 1998-01-01
Published in Mycopathologia. Dordrecht: Kluwer Academic Publ, v. 141, n. 2, p. 65-68, 1998.
ISSN 0301-486X (Sherpa/Romeo, impact factor)
Publisher Kluwer Academic Publ
Extent 65-68
Origin http://dx.doi.org/10.1023/A:1006951619245
Access rights Closed access
Type Article
Web of Science ID WOS:000075825700002
URI http://repositorio.unifesp.br/handle/11600/25845

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