Studies of antithyroid antibodies in Down's syndrome

Studies of antithyroid antibodies in Down's syndrome

Alternative title Anticorpos antitireóide na síndrome de Down
Author Schmidt, B. J. Autor UNIFESP Google Scholar
Piva, S. Autor UNIFESP Google Scholar
Schalch, A. L. O. Google Scholar
Ortega, C. Google Scholar
Sousa, M. M. Google Scholar
Torres, D. B. Google Scholar
Krynski, S. Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Centro de Habilitação de São Paulo
Abstract The presence of antithyroid antibodies (antithyroglobulin and antimicrosomal) in the serum of patients with Down's syndrome and their respective mothers were studied based on data from the literature, showing a possible correlation between the presence of these antibodies in the serum of mothers and the birth of mongoloid children. Antithyroid antibodies were studied in 40 patients with Down's syndrome, with ages ranging from 5 months to 21 years old, 24 males and 16 females and in the respective mothers whose ages varied from 22 to 66 years. In none of the analyzed sera of the mongoloids as well of their mothers, the authors were able to detect the antithyroid antibodies studied.

Foi estudado no soro de pacientes com síndrome de Down e suas respectivas mães, a presença de anticorpos antitireóide (antitireoglobulina e antimicrossomal), tendo em vista dados de literatura mostrando uma eventual correlação entre a presença destes anticorpos, no soro de mães com filhos, mongolóides. Os anticorpos antitireoideanos foram dosados em 40 pacientes com síndrome de Down, cuja idades variavam 5 meses a 21 anos, sendo 24 masculinos e 16 femininos e, nas respectivas mães, cujas idades variaram de 22 a 66 anos de idade. Em nenhum dos soros analisados, quer dos mongolóides bem como de suas respectivas mães, conseguiu-se detectar os anticorpos antitireoideanos estudados.
Language English
Date 1978-12-01
Published in Arquivos de Neuro-Psiquiatria. Academia Brasileira de Neurologia - ABNEURO, v. 36, n. 4, p. 312-315, 1978.
ISSN 0004-282X (Sherpa/Romeo)
Publisher Academia Brasileira de Neurologia - ABNEURO
Extent 312-315
Origin http://dx.doi.org/10.1590/S0004-282X1978000400003
Access rights Open access Open Access
Type Article
SciELO ID S0004-282X1978000400003 (statistics in SciELO)
URI http://repositorio.unifesp.br/handle/11600/172

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