Malignant transformation of pleomorphic xanthoastrocytoma: case report

Malignant transformation of pleomorphic xanthoastrocytoma: case report

Alternative title Transformação maligna de xantoastrocitoma pleomórfico: relato de caso
Author Tella Junior, Oswaldo Ignácio de Autor UNIFESP Google Scholar
Herculano, Marco Antonio Google Scholar
Prandini, Mirto Nelso Autor UNIFESP Google Scholar
Stávale, João Norberto Autor UNIFESP Google Scholar
Aguiar, Paulo Henrique Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Jundiai Medicine School Neurosurgical Department
State University of São Paulo Neurosurgical Department
Abstract We report a case of a pleomorphic xantoastrocytoma which manifested itself as a cystic isodense lesion in the right fronto-temporal lobe in a 26 year-old woman. It appeared as a soft yellow tumor with cystic cavities on surgery. Five months after this surgery, the patient was submitted to a new operation, which revealed a friable tumor, easily differentiated from the normal parenchyma, with cystic components. The histopathological examination demonstrated pleomorphic xanthoastrocytoma with malignant transformation. Histologically, the tumor at first procedure was composed of pleomorphic astrocytes with multinucleated and foamy cells. A rare case of malignant transformation in pleomorphic xanthoastrocytoma is presented, discussed and illustrated in this paper.

Um caso raro de transformação maligna de xantoastrocitoma pleomórfico é apresentado, discutido e ilustrado neste estudo. Descrevemos um caso de xantoastrocitoma pleomórfico diagnosticado como lesão isodensa no lobo fronto-temporal direito, em uma paciente de 26 anos. Na cirurgia, encontrou-se tumor mole, de cor amarelada, com cavidade cística. Cinco meses após o procedimento, a paciente foi submetida a nova intervenção que revelou um tumor friável, facilmente diferenciado do parênquima normal, com componentes císticos. O exame histopatológico demonstrou um xantoastrocitoma pleomórfico com transformação maligna. O tumor, no primeiro procedimento, era formado por astrócitos pleomórficos com células vacuolizadas e multinucleadas.
Keywords xanthoastrocytoma
astrocytoma
tumor
histopathology
xantoastrocitoma
astrocitoma
tumor
histopatologia
Language English
Date 2003-03-01
Published in Arquivos de Neuro-Psiquiatria. Academia Brasileira de Neurologia - ABNEURO, v. 61, n. 1, p. 104-106, 2003.
ISSN 0004-282X (Sherpa/Romeo, impact factor)
Publisher Academia Brasileira de Neurologia - ABNEURO
Extent 104-106
Origin http://dx.doi.org/10.1590/S0004-282X2003000100020
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000182336700020
SciELO ID S0004-282X2003000100020 (statistics in SciELO)
URI http://repositorio.unifesp.br/handle/11600/1676

Show full item record




File

Name: S0004-282X2003000100020.pdf
Size: 242.0Kb
Format: PDF
Description:
Open file

This item appears in the following Collection(s)

Search


Browse

Statistics

My Account