Studies of the thyroid function in children with Down's syndrome

Studies of the thyroid function in children with Down's syndrome

Alternative title Estudos da função tireóidea em crianças com síndrome de Down
Author Schmidt, Benjamin J. Autor UNIFESP Google Scholar
Carvalho, Nelson Google Scholar
Ortega, Cláudio C. Google Scholar
Libermam, José Google Scholar
Biazzi, Jane M. M. Google Scholar
Tapajós, Pojucan M. Google Scholar
Krynski, Stanislau Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Universidade de São Paulo (USP)
Centro de Habilitação de São Paulo
Abstract The thyroid function (T-3 triiodothyronine; T-4 tetraiodothyronine and the captation of the I131 through the thyroid, in 2 and 24 hours after the intake of isotope radium), was studied in patients with Down's syndrome and the results being compared to those obtained from the respective siblings, all clinically normal. The comparative results showed no significant differences, except in the 2 hours captation of the I131 through the thyroid (P < 0.01). The findings suggest that the hypothalamus-hypophysary or the response of the thyroid gland would be slow, but compensated when analyzed after 24 hours.

Os autores estudaram a função tireóidea (T-3, triiodotironina; T-4, tetraiodotironina e captação do I131 pela tireóide com 2 e 24 horas após a ingestão do radioisótopo) em pacientes com síndrome de Down, e compararam os resultados com os obtidos nos seus respectivos irmãos, todos clinicamente normais. Os resultados comparativos não apresentaram diferenças significativas, exceto na captação de 2 horas do I131 pela tireóide (P < 0,01). Os achados sugerem que o estímulo hipotálamo hipofisário ou a resposta da glândula tireóide seria lento (a) mas compensado (a) quando analisados após 24 horas.
Language English
Date 1975-03-01
Published in Arquivos de Neuro-Psiquiatria. Academia Brasileira de Neurologia - ABNEURO, v. 33, n. 1, p. 21-24, 1975.
ISSN 0004-282X (Sherpa/Romeo)
Publisher Academia Brasileira de Neurologia - ABNEURO
Extent 21-24
Origin http://dx.doi.org/10.1590/S0004-282X1975000100002
Access rights Open access Open Access
Type Article
SciELO ID S0004-282X1975000100002 (statistics in SciELO)
URI http://repositorio.unifesp.br/handle/11600/159

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