Effect of the acupoints ST-36 (Zusanli) and SP-6 (Sanyinjiao) on intestinal myoelectric activity of Wistar rats

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dc.contributor.author Tabosa, Angela Maria Florencio [UNIFESP]
dc.contributor.author Yamamura, Ysao [UNIFESP]
dc.contributor.author Forno, E.r. [UNIFESP]
dc.contributor.author Mello, Luiz Eugenio Araujo de Moraes [UNIFESP]
dc.date.accessioned 2015-06-14T13:29:44Z
dc.date.available 2015-06-14T13:29:44Z
dc.date.issued 2002-06-01
dc.identifier http://dx.doi.org/10.1590/S0100-879X2002000600015
dc.identifier.citation Brazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 35, n. 6, p. 731-739, 2002.
dc.identifier.issn 0100-879X
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/1465
dc.description.abstract Despite its ancient use as a therapeutic tool to treat several ailments, acupuncture still faces the challenge of scrutiny by Western science both in terms of its efficacy and in terms of the characterization of its effects and mechanisms of actions underlying these effects. We investigated under well-controlled and carefully characterized conditions the influence of electrical stimulation of acupuncture points ST-36 (Zusanli) and SP-6 (Sanyinjiao) on the myoelectric activity of the small intestine of 38 adult male Wistar rats. Electrical recordings obtained by means of four electrodes chronically implanted in the small intestine were used to assess the effects of acupuncture (electroacupuncture stimulation set at 2 Hz, intermittent stimulation, 1 V, for 30 min). Immobilization of the animals was associated with a consistent decrease (-8 ± 7%) in the myoelectric activity of the small intestine as measured by means of the root mean square. Conversely, acupuncture was able to significantly increase (overshoot) this activity compared to baseline (+44 ± 7%). In contrast, immobilized animals subjected to sham acupuncture had only modest (nonsignificant) increases in myoelectric activity (+9 ± 6%). Using carefully controlled conditions we confirmed previous noncontrolled studies on the ability of acupuncture to alter intestinal motility. The characterization of the topographic and temporal profiles of the effects observed here represents a basis for future dissection of the physiological and pharmacological systems underlying these effects. en
dc.format.extent 731-739
dc.language.iso eng
dc.publisher Associação Brasileira de Divulgação Científica
dc.relation.ispartof Brazilian Journal of Medical and Biological Research
dc.rights Acesso aberto
dc.subject Acupuncture en
dc.subject Intestinal motility en
dc.subject Rat en
dc.subject Myoelectric activity en
dc.subject Acupuncture point en
dc.title Effect of the acupoints ST-36 (Zusanli) and SP-6 (Sanyinjiao) on intestinal myoelectric activity of Wistar rats en
dc.type Artigo
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.description.affiliation Universidade Federal de São Paulo (UNIFESP) Departamento de Ortopedia e Traumatologia Divisão de Medicina Chinesa e Acupuntura
dc.description.affiliation Universidade Federal de São Paulo (UNIFESP) Departamento de Fisiologia
dc.description.affiliationUnifesp UNIFESP, Depto. de Ortopedia e Traumatologia Divisão de Medicina Chinesa e Acupuntura
dc.description.affiliationUnifesp UNIFESP, Depto. de Fisiologia
dc.identifier.file S0100-879X2002000600015.pdf
dc.identifier.scielo S0100-879X2002000600015
dc.identifier.doi 10.1590/S0100-879X2002000600015
dc.description.source SciELO
dc.identifier.wos WOS:000176452400015



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